KMID : 0616120120430030257
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Korean Journal of Pharmacognosy 2012 Volume.43 No. 3 p.257 ~ p.264
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Establishment of Shelf-life of Ssanghwa-tang by Long-term Storage Test
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Seo Chang-Seob
Kim Jung-Hoon Lim Soon-Hee Shin Hyeun-Kyoo
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Abstract
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The purpose of this study was to estimate the shelf-life of Ssanghwa-tang by long-term storage test. Experiments were conducted to evaluate the stability such as the selected physicochemical, pH, identification, heavy metal, microbiological experiment under a long-term storage test of Ssanghwa-tang. The significant change was not showed in pH, heavy metal, microbiological, identification test and quantitative analysis based on long-term storage test. The contents of albiflorin, paeoniflorin, cinnamic acid, liquiritin, and glycyrrhizin in long-term storage test were 66.8-93.1 , 429.0-495.0 , 3.8-4.4 , 32.0-38.1 , and 66.8-71.7 , respectively. Shelf-lifes by 5 compounds about 3 lots at room temperature were predicted 21-37, 14-21, and 16-72 months, respectively. The suggested shelf-life would be helpful on the storage and distribution of herbal medicine.
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KEYWORD
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Shelf-life, Ssanghwa-tang, Long-term storage test, Herbal medicine
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